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CPAP Therapy and Atrial Fibrillation Recurrence in OSA

NCT07358429 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 91

Last updated 2026-01-22

No results posted yet for this study

Summary

Obstructive sleep apnea (OSA) is a major modifiable risk factor for atrial fibrillation (AF). Continuous positive airway pressure (CPAP) therapy has been shown to improve cardiovascular outcomes; however, real-world data on its effect on AF recurrence remain limited.

This prospective cohort study aims to evaluate the association between objective CPAP adherence and the risk of AF recurrence in patients with moderate-to-severe OSA and a history of paroxysmal AF.

Patients will be followed for 12 months, with AF recurrence assessed using electrocardiography and Holter monitoring.

Conditions

  • Obstructive Sleep Apnea (OSA)
  • Atrial Fibrillation (Paroxysmal)

Interventions

DEVICE

Continuous Positive Airway Pressure (CPAP)

CPAP therapy is initiated according to standard clinical practice. Objective adherence data (mean nightly usage, percentage of nights ≥ 4 hours) are collected via telemonitoring systems.

Sponsors & Collaborators

  • Medical University of Sofia

    lead OTHER

Principal Investigators

  • Petar R Kalaydzhiev, PhD · Medical University - Sofia

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-01
Primary Completion
2025-11-30
Completion
2027-12-30

Countries

  • Bulgaria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07358429 on ClinicalTrials.gov