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The Effect of 16-week Dietary Intake of Food Supplements Containing Collagen and MSM on Facial Erythema and Other Skin Parameters

NCT07345195 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-01-15

No results posted yet for this study

Summary

The aim of this study is to compare the effects of 16 weeks of daily dietary supplementation with two investigational products containing collagen, methylsulfonylmethane (MSM), and vitamin C on skin parameters in comparison to a placebo product. The study will be conducted in healthy human subjects with visible facial erythema and telangiectasiae (cheeks), stable for ≥3 months, without active rosacea.

The primary objective is to demonstrate beneficial effects of the investigational products on facial erythema.

The secondary objective is to evaluate the effect of the investigational products on facial telangiectasiae severity.

Other skin parameters will be assessed as supportive endpoints, and differences in efficacy between the two investigational formulations will also be evaluated.

Conditions

  • Erythema
  • Telangiectasis
  • Skin Redness

Interventions

DIETARY_SUPPLEMENT

CPMSM-HD

Participants will test continuous administration of investigational product for 16 weeks.

DIETARY_SUPPLEMENT

CPMSM-LD

Participants will test continuous administration of the investigational product for 16 weeks.

DIETARY_SUPPLEMENT

Placebo

Participants will test continuous administration of placebo product for 16 weeks.

Sponsors & Collaborators

  • Tosla d.o.o.

    collaborator INDUSTRY

  • Slovenian Research Agency

    collaborator OTHER

  • VIST - Faculty of Applied Sciences

    lead OTHER

Principal Investigators

  • Katja Žmitek, PhD · Head of Reasearch Group

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
65 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-31
Primary Completion
2026-09-30
Completion
2026-11-30

Countries

  • Slovenia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07345195 on ClinicalTrials.gov