MedTrace Logo

The Effect of Methylsulfonylmethane (MSM) on Cardiometabolic Health

NCT03716791 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 43

Last updated 2021-10-05

No results posted yet for this study

Summary

Obesity- related diseases are linked to elevated levels of inflammation, oxidative stress, and metabolic dysfunction. Methylsulfonylmethane (MSM) is a naturally occurring compound that demonstrates antioxidant and anti-inflammatory effects. Improvements in measures of metabolic health have been observed in mouse models of obesity and type 2 diabetes following MSM treatment. However, the effect of MSM on obesity-related risk factors for disease in humans has not been investigated. Therefore, the purpose of this investigation will be to determine whether MSM supplementation improves metabolic health, and markers of inflammation and oxidative status.

Conditions

Interventions

DIETARY_SUPPLEMENT

methylsulfonylmethane

3g per day

DIETARY_SUPPLEMENT

placebo

white rice flour

Sponsors & Collaborators

  • Lindsey Miller

    lead OTHER

Principal Investigators

  • Lindsey E Miller, Ph.D · Washington State University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-02-19
Primary Completion
2021-01-30
Completion
2021-08-11

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03716791 on ClinicalTrials.gov