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Positional Effects on Lung Ventilation and Perfusion in Obesity

NCT07341113 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2026-04-15

No results posted yet for this study

Summary

Electrical Impedance Tomography (EIT) is a non-invasive, bedside monitoring tool that provides real-time information on regional ventilation and perfusion. In particular, EIT has the potential to guide individualized mechanical ventilation in obese patients by revealing how gravitational and positional factors alter regional lung behavior. Assessing the effects of different horizontal positions on both ventilation and perfusion may help optimize respiratory management strategies tailored to body habitus. By comparing obese and non-obese healthy participants across different positions, this study aims to provide novel insights into the postural effects on lung aeration and perfusion distribution, and to highlight the role of EIT in tailoring individualized ventilation strategies.

Conditions

  • Obesity (Disorder)
  • Ventilation Homogeneity
  • Perfusion
  • Ventilation Perfusion Mismatch
  • Position Differences
  • Electrical Impedance Tomography (EIT)

Interventions

OTHER

Standardized body positioning

Standardized changes in body position (supine, Trendelenburg, prone, and lateral positions) performed solely for physiologic assessment of ventilation and perfusion using electrical impedance tomography. This does not constitute a therapeutic or preventive intervention.

Sponsors & Collaborators

  • Koç University

    lead OTHER

Principal Investigators

  • Evren Şentürk, MD · Koç University School of Medicine

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-01
Primary Completion
2026-03-05
Completion
2026-03-05

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07341113 on ClinicalTrials.gov