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Combining Electrical Impedance Tomography and Thoracic Ultrasound Toinvestigate Dynamic Changes

NCT06958770 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2025-05-06

No results posted yet for this study

Summary

1. To evaluate the dynamic changes of lung ultrasound during electrical impedance tomography (EIT) PEEP titration and across the first week of ARDS.
2. To asses respiratory effort by diaphragmatic function, esophageal pressure, and EIT (Pendelluft phenomenon), and hyperinflammatory biomarkers, to predict P-SILI.
3. To develop predictive models for weaning success based on integrated EELI and thoracic ultrasound.

Conditions

  • ARDS (Moderate or Severe)

Interventions

DIAGNOSTIC_TEST

Electrical impedance tomography

* Electrical impedance tomography (EIT)：Assessing pulmonary function in chronic lung diseases. * Lung ultrasound：Assessing diaphragm atrophy in mechanically ventilated patients. * Esophageal pressure：The work of breathing, or the energy required by respiratory muscles to meet ventilatory demands, can be directly evaluated by esophageal pressure * Oxygen consumption：Indirectly evaluated by measuring oxygen consumption (V̇O2) during mechanical ventilation The oxygen cost of breathing, reflected the increase in V̇O2 when transitioning from mechanical ventilation to spontaneous breathing, has been shown to predict weaning outcomes.

Sponsors & Collaborators

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Yao-Wen Kuo · National Taiwan University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-19
Primary Completion
2028-12-31
Completion
2028-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06958770 on ClinicalTrials.gov