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Post- End- Expiratory Pressure Affect the Alveolar Heterogeneity in Moderate and Sever ARDS Patients

NCT03763890 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2022-07-19

No results posted yet for this study

Summary

This study try to use EIT ( Electronic impedance tomography ) to evaluate the alveolar heterogeneity and use trans-pulmonary pressure and stain to evaluate the lung injury . The study use these methods to figure out how PEEP impact the alveolar heterogeneity and VILI.

Conditions

  • Ards

Interventions

DEVICE

Post-end-Expiratory pressure

Titrate the PEEP from 24 cmH2O to 6 cmH2O, 2 cmH2O/step and record EIT, trans-pulmonary pressure, hemodynamic parameter and Blood-gas analysis.

Sponsors & Collaborators

  • Southeast University, China

    lead OTHER

Principal Investigators

  • haibo qiu, PhD · Nanjing Zhong-Da Hospital, Southeast University School of Medicine,China

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2023-12-30
Completion
2023-12-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03763890 on ClinicalTrials.gov