Sensory Mechanisms of Manual Dexterity Recovery After Stroke: a Prospective Cohort Study of Prediction and Cerebral Correlates
NCT07340736 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2026-01-14
Summary
In the proposed research, we will assess motor and sensory functions of the hand using clinical tests and a tool designed to measure manual dexterity combined with vibrotactile stimulation. We will also evaluate the integrity of brain structure and function using MRI.
Conditions
- Stroke
- Upper Extremity Paresis
- Manual Dexterity
- Sensory Integration Dysfunction
- Vibration
Interventions
- DEVICE
-
Haptic stimulation device
Both patients and healthy participants will perform manual dexterity tasks using the Dextrain Manipulandum. In addition, they will receive finger vibrations delivered via rings that we have previously developed. These vibrations will have a frequency of 150 Hz and will be delivered for a duration of 150 ms.
- OTHER
-
Brain MRI
Subjects and patients will undergo anatomical, resting-state functional, and diffusion brain MRI sequences.
Sponsors & Collaborators
-
Centre Hospitalier St Anne
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-03-01
- Primary Completion
- 2028-03-01
- Completion
- 2028-03-01
Countries
- France
Study Locations
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