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Echocardiography Findings in Patients With Myocardial Fibrosis and Severe Aortic Stenosis

NCT07331116 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 22

Last updated 2026-04-17

No results posted yet for this study

Summary

Patients with aortic stenosis waiting for aortic valve repair were investigated with echocardiography preoperatively, and a myocardial biospy was taken during the operation. The investigators aim to perform a retrospective analysis of these data, to look for correlations between biopsy-verified myocardial fibrosis and echocardiography parameters.

The patients also had cardiac magnetic resonance imaging performed, for a non-invasive quantification of myocardial fibrosis.

Conditions

  • Aortic Valve Stenosis
  • Myocardial Fibrosis

Interventions

DIAGNOSTIC_TEST

Transthoracic echocardiography

Transthoracic echocardiography, performed close in time to the endomyocardial biopsy taken during aortic valve replacement procedure

DIAGNOSTIC_TEST

Cardiac magnetic resonance imaging

Cardiac magnetic resonance imaging was taken on selected patients without contraindications. The CMR protocol was changed midway during study inclusions (May 2017), in order to better be able to quantify myocardial fibrosis.

Sponsors & Collaborators

  • Rikshospitalet University Hospital

    collaborator OTHER

  • Norwegian University of Science and Technology

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-04-10
Primary Completion
2021-02-16
Completion
2021-03-01

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07331116 on ClinicalTrials.gov