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Improving Echo Measurements in the Diagnosis of Aortic Stenosis

NCT02146755 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 396

Last updated 2017-06-12

No results posted yet for this study

Summary

Aortic stenosis is a common valvular heart disease, affecting mainly people over age 60. It is characterized by years to decades of slow progression followed by rapid clinical deterioration and a high death rate once symptoms develop. The onset of symptoms confers a poor prognosis: patients die within an average of five years after the onset of angina, three years after the onset of syncope, and two years after the onset of heart failure symptoms. The overall mortality rate is 75% at three years without surgery. Drug therapy for it remains ineffective, and aortic valve replacement is the only recommended long-term treatment.

Conditions

  • Aortic Valve Stenosis

Sponsors & Collaborators

  • Baylor Research Institute

    lead OTHER

Principal Investigators

  • Paul Grayburn, MD · Baylor Research Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2015-12-31
Completion
2015-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02146755 on ClinicalTrials.gov