Early Detection of Cardiac Amyloidosis
NCT05010980 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400
Last updated 2022-10-31
Summary
Due to a lack of therapeutic options, the diagnosis of cardiac (wt)-ATTR amyloidosis was for a long time overshadowed by other diseases and therefore was or still is often diagnosed with considerable delay.
The aim of the study is to estimate the prevalence of cardiac amyloidosis among patients with mild-to-moderate aortic valve stenosis (AS).
Besides that a screening algorithm based on echocardiographic parameters will be developed, to facilitate the early detection of cardiac amyloidosis.
Conditions
- Amyloidosis
- Aortic Valve Stenosis
Interventions
- OTHER
-
CMR
clinical indication
- OTHER
-
scintigraphy
clinical indication
Sponsors & Collaborators
-
Heinrich-Heine University, Duesseldorf
lead OTHER
Principal Investigators
-
Ralf Westenfeld, MD · Division. of Cardiology, Pulmonary Disease and Vascular Medicine
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-08-01
- Primary Completion
- 2023-09-30
- Completion
- 2023-09-30
Countries
- Germany
Study Locations
More Related Trials
-
Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology
NCT03842163 ·Status: COMPLETED
-
The Regional Scintigraphic DPD Uptake in Cardiac Transthyretin Amyloidosis.
NCT05814380 ·Status: UNKNOWN
-
Radioisotope Scintigraphy to Establish Incidence of Cardiac Amyloidosis Among Patients With Otherwise Unexplained Cardiac Disease
NCT03098901 ·Status: UNKNOWN ·Phase: NA
-
Prevalence of Transthyretin Amyloidosis in Hypertrophic Cardiomyopathy
NCT01623245 ·Status: COMPLETED
-
Transthyretin Cardiac Amyloidosis in HFpEF
NCT03414632 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
PL_GNT01_ISR_Grant 53234273
NCT06714019 ·Status: ENROLLING_BY_INVITATION
-
Dobutamine Stress Echocardiography in LF/LG Aortic Stenosis and Wild-type Transthyretin Amyloid Cardiomyopathy
NCT06372301 ·Status: RECRUITING ·Phase: NA
-
Increasing Amyloidosis Awareness and Diagnosis Through Programmatic Imaging, Blood/Urine Testing and Pathology
NCT04983433 ·Status: UNKNOWN
-
Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations
NCT03812172 ·Status: COMPLETED
-
Myocardial Ischemia Detection With a Combined Cardiovascular Magnetic Resonance and Biomarker Protocol
NCT05813210 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Diagnostic Yield of Cardiac CT to Detect Cardiac Thrombi in Acute Ischemic Stroke: an Individual Patient Data Meta-Analysis
NCT07165093 ·Status: COMPLETED
-
High Resolution Three-dimensional Maps of the Right Chambers in Patient Diagnosed With Cardiac Amyloidosis
NCT04956965 ·Status: UNKNOWN ·Phase: NA
-
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) in Patients With Idiopathic Peripheral Neuropathy
NCT04985734 ·Status: UNKNOWN ·Phase: NA
-
A Multi-center Cardiac PYP Scan Registry in Taiwan
NCT05593679 ·Status: RECRUITING
-
Echocardiographic Characterization of Cardiac Amyloidosis
NCT05760287 ·Status: RECRUITING
-
Artificial Intelligence Enhanced ECG to Detect Cardiac Amyloidosis
NCT05557162 ·Status: COMPLETED ·Phase: NA
-
Prevalence of Cardiac Amyloidosis Among Patients With a History of Lumbar Spinal Stenosis.
NCT05701410 ·Status: UNKNOWN ·Phase: NA
-
Cardiac Amyloidosis in HFpEF Tunisian Patients
NCT06201832 ·Status: COMPLETED
-
Biological Variation of Cardiac Biomarkers in Aortic Valve Stenosis
NCT02510482 ·Status: COMPLETED
-
Amyloidosis TTR Flow Reserve Evaluation
NCT05103943 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Cardiac Amyloidosis Registry Study
NCT05174338 ·Status: ENROLLING_BY_INVITATION
-
Prevalence of Cardiac Amyloidosis in Patients Undergoing Surgery for Lumbar Spinal Stenosis.
NCT05701397 ·Status: UNKNOWN ·Phase: NA
-
Prevalence and Prognosis of Cardiac Amiloidosis in Turkey
NCT04915235 ·Status: RECRUITING
-
Phenotypic Manifestations of Hereditary ATTR Amyloidosis
NCT07124377 ·Status: RECRUITING
-
Identification of Prognostic Parameters in Patients With " Senile " Amyloid Cardiomyopathy
NCT04225754 ·Status: UNKNOWN