Stroke Imaging Package Study of Intracranial Atherosclerosis ( SIPS-ICAS )

Summary

A prospective, multicenter, cohort study to explore the stroke mechanisms of symptomatic intracranial atherosclerosis, the dynamic changes under aggressive medical treatment and their associations with clinical events using conventional MRI sequences plus high-resolution magnetic resonance (HR-MRI).

Conditions

• Acute Ischemic Stroke AIS
• Intracranial Atherosclerosis ICAS

Interventions

DRUG

aggressive medical management

Aspirin (100 mg daily) and Clopidogrel (75 mg daily) for 3 months and Rosuvastatin (20mg daily) for at least 6 months as well as traditional risk factors management

Sponsors & Collaborators

• Peking Union Medical College Hospital

  collaborator OTHER

• General Hospital of Chinese Armed Police Forces

  collaborator OTHER

• General Hospital of Shenyang Military Region

  collaborator OTHER

• Subei People's Hospital of Jiangsu Province

  collaborator OTHER

• Fujian Medical University Union Hospital

  collaborator OTHER

• Tangshan Gongren Hospital

  collaborator OTHER

• Third Affiliated Hospital, Sun Yat-Sen University

  collaborator OTHER

• Qingdao Municipal Hospital

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Shanghai Tong Ren Hospital

  collaborator OTHER

• Ruijin Hospital

  collaborator OTHER

• The First Affiliated Hospital of University of South China

  collaborator OTHER

• JiNing NO.1 People Hospital

  collaborator UNKNOWN

• Tongji Hospital

  collaborator OTHER

• The University of HongKong-Shenzhen Hospital

  collaborator UNKNOWN

• Beijing Anzhen Hospital

  collaborator OTHER

• Beijing Hospital

  collaborator OTHER_GOV

• Peking University International Hospital

  collaborator OTHER

• Beijing Tongren Hospital

  collaborator OTHER

• China-Japan Friendship Hospital

  collaborator OTHER

• Peking University First Hospital

  collaborator OTHER

• Beijing Friendship Hospital

  collaborator OTHER

• Beijing Chao Yang Hospital

  collaborator OTHER

• Qilu Hospital of Shandong University (Qingdao)

  collaborator OTHER

• Shandong Provincial Hospital

  collaborator OTHER_GOV

• The Second Hospital of Hebei Medical University

  collaborator OTHER

• Hebei General Hospital

  collaborator OTHER

• First Affiliated Hospital of Zhejiang University

  collaborator OTHER

• China-Japan Union Hospital, Jilin University

  collaborator OTHER

• Zhejiang Provincial Tongde Hospital

  collaborator OTHER

• People's Hospital of Ningxia Hui Autonomous Region

  collaborator OTHER

• Taiyuan Central Hospital of Shanxi Medical University

  collaborator OTHER

• Hong Xinglong Central Hospital

  collaborator UNKNOWN

• Changzhi People's Hospital

  collaborator OTHER

• Weihai Municipal Hospital

  collaborator OTHER

• Southwest Hospital, China

  collaborator OTHER

• Affiliated Taihe Hospital of Hubei University of Medicine

  collaborator UNKNOWN

• Nanshi Hospital of Nanyang

  collaborator UNKNOWN

• Wei-Hai Xu

  lead OTHER

Principal Investigators

• Weihai Xu, MD · Peking Union Medical College Hospital

Eligibility

Min Age

35 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-11-14

Primary Completion

2020-12-31

Completion

2021-06-30

Countries

• China

Study Locations