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Sucrase-Isomaltase (SI) Genes and Meal Load

NCT07309601 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2026-04-29

No results posted yet for this study

Summary

The goal of this interventional study is to examine whether those patients with irritable bowel syndrome (IBS) and a reduced abitility do degrade starch and sugar (lowe levels of enzymes) have lower raise in blood glucose after a meal than those with normal expression of enzymes. We also want to examine whether those IBS patients with reduced enzyme levels have increased bowel symptom in relation to this meal.

The main questions it aims to answer are:

Does reduced ability to degrade starch and sugar due to less enzyme activity lead to lower increase in blood glucose after a meal? Does reduced ability to degrade starch and sugar due to less enzyme activity lead to increased bowel symptoms after a meal?

Conditions

  • IBS - Irritable Bowel Syndrome
  • Sucrase-Isomaltase Deficiency

Interventions

DIETARY_SUPPLEMENT

Meal load

Meal load during 15 minutes

Sponsors & Collaborators

  • Region Skane

    lead OTHER

Principal Investigators

  • Cecilia Kennbäck, Registered Nurse · Department of Internal Medicine, Skåne University Hospital, 20502 Malmö

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-01
Primary Completion
2028-02-01
Completion
2030-02-01

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07309601 on ClinicalTrials.gov