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The Effect of Sugar Load in IBS Patients Depending on Sucrase-isomaltase Genes

NCT05688826 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2025-06-27

No results posted yet for this study

Summary

The investigators know that many patients with irritable bowel syndrome (IBS) have functional variants of genes coding for sucrase-isomaltase enzymes. The investigators will now examine whether these functional variants are associated with defect degradation of sucrose and associated gastrointestinal symptoms

Conditions

  • Sucrase-Isomaltase Deficiency
  • Irritable Bowel Syndrome

Interventions

DIETARY_SUPPLEMENT

Sugar

75 g sugar dissolved in 0.8 dl water and flavored with lemon. Ingested during 5 minutes

Sponsors & Collaborators

  • Region Skane

    lead OTHER

Principal Investigators

  • Cecilia Kennback, Nurse · Department of Internal Medicine, Skåne University Hospital, Malmö

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-04
Primary Completion
2023-09-27
Completion
2025-06-23

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05688826 on ClinicalTrials.gov