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Effect of Chronic Exercise on Human Thermogenic Adipose Tissue & Elucidation of Mechanisms

NCT07299604 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2025-12-23

No results posted yet for this study

Summary

Physical exercise can stimulate heat production in our bodies. This is healthy because it burns sugar and fat. Heat production is influenced, among other things, by what is known as 'brown or beige adipose tissue', which is capable of producing heat in our bodies. However, everyone reacts differently to physical exercise. In addition, different types of exercise can influence heat production. That is why the investigators want to use this study to investigate why different people show different reactions in brown and beige adipose tissue. This is important for our metabolism and our health.

The study will last approximately 6 weeks. The participants are healthy individuals who are participating in the study. The test subjects will be divided into two groups by drawing lots, so that there are equal numbers of men and women in each group.

One group will complete a 6-week endurance training programme. The other group (control) will not do any additional training and will serve as a control group. However, the accompanying examinations will be the same for both groups. By comparing the two groups, the investigators will be able to see whether training has a better effect on heat production and thus health.

As part of this study, the investigators want to investigate how 6 weeks of endurance training affects the function of brown and beige adipose tissue. To do this, the investigators will take some blood and adipose tissue samples before and after the training period.

Conditions

  • Endurance Training
  • No Training

Interventions

BEHAVIORAL

Endurance Training

6 weeks of endurance training, 3time per week

Sponsors & Collaborators

  • German Research Foundation

    collaborator OTHER

  • University Hospital, Bonn

    collaborator OTHER

  • Helmholtz Center Munich

    collaborator UNKNOWN

  • Technical University of Munich

    lead OTHER

Principal Investigators

  • Alexander Braunsperger, PhD candidate · Technical University Munich, Professorship of Exercise Biology, Am Olympacampus 11, 80809 Munich

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2025-06-30
Completion
2025-06-30

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07299604 on ClinicalTrials.gov