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Mechanisms of Maternal Immune Tolerance in Early Pregnancy

NCT07297394 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-03-04

No results posted yet for this study

Summary

This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester. The goal is to identify immunological factors that support healthy gestation and prevent complications such as miscarriages.

Conditions

  • Pregnancy
  • Immune Tolerance
  • In Vitro Fertilization

Interventions

OTHER

Blood sampling

Blood samples will be analyzed before and during early pregnancy as well as after early miscarriage

Sponsors & Collaborators

  • University Hospital, Basel, Switzerland

    lead OTHER

Principal Investigators

  • Ursula Gobrecht-Keller, MD · University Hospital of Basel

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-02
Primary Completion
2030-12-31
Completion
2030-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07297394 on ClinicalTrials.gov