Immunomodulation During Pregnancy
NCT06882850 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30
Last updated 2025-03-19
Summary
The goal of this observational study is to learn about the effects of low dose aspirin in immunity Pregnant women taking aspirin for other reasons (preeclampsia prevention) will be studied. The main question it aims to answer is: evaluate the effect of LDA on the modulation of innate immunity cells (NK cells, monocytes, γδ T cells) and/or acquired immunity (B and T lymphocytes, Treg cells, Th cells).
Participants already taking intervention A as part of their regular medical care for RA will answer online survey questions about their joint pain for 5 years.
Conditions
- Aspirin
- Pregnancy Complications
- Immunology
Sponsors & Collaborators
-
Unidade Local de Saúde de Coimbra, EPE
lead OTHER
Principal Investigators
-
Ana L Areia, PhD MD · University of Coimbra
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-02-01
- Primary Completion
- 2025-03-30
- Completion
- 2025-03-31
Countries
- Portugal
Study Locations
More Related Trials
-
Antenatal Platelet Response on Aspirin: a Pharmacokinetic Study Through Pregnancy
NCT04645004 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Aspirin (ASA) Therapy and Preeclampsia Prevention
NCT04158830 ·Status: WITHDRAWN ·Phase: PHASE4
-
Early Prediction and Randomised Prevention of Preeclampsia With Low Dose Aspirin in Chinese Cohort
NCT04631627 ·Status: UNKNOWN ·Phase: PHASE4
-
Antenatal Platelet Response On Aspirin and Correlation With HDP (Hypertensive Disorders of Pregnancy)
NCT04295850 ·Status: COMPLETED
-
Aspirin 150 mg vs 100 mg for Prevention of Preeclampsia in High-Risk Obese Pregnant Women
NCT06952712 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers
NCT01729468 ·Status: COMPLETED ·Phase: PHASE4
-
Aspirin for the Prevention of Preeclampsia and Pregnancy Outcomes After Assisted Reproductive Technology
NCT05625724 ·Status: RECRUITING ·Phase: PHASE3
-
Low Dose Aspirin for Preterm Preeclampsia Preventionmg/day Dose in High-risk Patients
NCT05514847 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
The Effectiveness of Aspirin on Preventing Pre-eclampsia
NCT04656665 ·Status: UNKNOWN ·Phase: PHASE4
-
Early Prevention of Preeclampsia Study
NCT01547390 ·Status: TERMINATED ·Phase: NA
-
Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)
NCT06826859 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Aspirin for Prevention of Preeclampsia
NCT03726177 ·Status: UNKNOWN ·Phase: NA
-
Aspirin Discontinuation in High-Risk Pregnant Women of Preeclampsia
NCT06111079 ·Status: RECRUITING ·Phase: PHASE3
-
Aspirin for Prevention of Preeclampsia in Healthy, Nulliparous Obese and Overweight Pregnant Women
NCT03725891 ·Status: UNKNOWN ·Phase: NA
-
The Investigation of the Prediction Model and Prevention Strategy of Serious Pregnancy Complications in Hypertensive Disorders of Pregnancy Based on the Chinese Population
NCT05089175 ·Status: UNKNOWN
-
Cardiac and Immune Cell Function in Preeclampsia
NCT04508582 ·Status: COMPLETED
-
Implementation of First-trimester Screening and preventiOn of pREeClAmpSia Trial (FORECAST)
NCT03941886 ·Status: COMPLETED ·Phase: NA
-
Effect of Hydroxytyrosol on NLR, MLR, and SOD in Hypertensive Pregnant Women
NCT07074548 ·Status: COMPLETED ·Phase: NA
-
Low Dose Aspirin in the Prevention of Preeclampsia in China
NCT02797249 ·Status: COMPLETED ·Phase: PHASE3
-
The Efficacy of Aspirin Combined With Hydroxychloroquine Treatment in High Risk Pregnancies for Preeclampsia
NCT05287321 ·Status: RECRUITING ·Phase: PHASE3
-
Adherence to Universal Aspirin Compared to Screening Indicated Aspirin for Prevention of Preeclampsia
NCT04797949 ·Status: WITHDRAWN ·Phase: PHASE4
-
Treatment With Aspirin After Preeclampsia: TAP Trial
NCT06281665 ·Status: RECRUITING ·Phase: PHASE4
-
Trial of Early Screening Test for Pre-eclampsia and Growth Restriction
NCT03674606 ·Status: COMPLETED ·Phase: PHASE4
-
Utilization of Aspirin for Prevention of Pre-Eclampsia in Nigeria: A Explanatory Sequential Mixed Methods Study
NCT06053203 ·Status: COMPLETED
-
Comparison of Doses of Acetylsalicylic Acid in Women With Previous History of Preeclampsia
NCT01352234 ·Status: COMPLETED ·Phase: PHASE4