Halt Aging in Survivors of Blood Cancers
NCT07292272 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 180
Last updated 2026-05-18
Summary
Older survivors of blood cancer are at a high risk of accelerated biological aging, which increases their risk of developing multiple aging-related conditions. Whereas physical exercise can improve overall health, older cancer survivors do not meet the recommended physical activity, highlighting the need to develop behavioral interventions to increase adherence. Several other knowledge gaps exist to implement exercise interventions in older survivors of blood cancer; the dose and duration of exercise necessary to slow biological aging in older blood cancer survivors remain unknown. To bridge these gaps in knowledge, we have designed a Phase 2 randomized control trial to test the effects of behavioral and exercise interventions on various outcomes.
Conditions
- Hematological Malignancy
- Leukemia
- Lymphoid Leukemia
- Multiple Myeloma
- Myeloid Leukemia
- Monocytic Leukemia
- Non-hodgkin Lymphoma
- Other Hematologic Condition
Interventions
- BEHAVIORAL
-
Behavioral Coaching Intervention
Intervention arm incorporating virtually supervised moderate-intensity aerobic exercise and behavioral intervention/coaching to improve adherence
- BEHAVIORAL
-
Virtual Exercise Platform
Access to a virtual exercise platform that provides exercise classes and educational sessions for older survivors of blood cancer
Sponsors & Collaborators
-
University of Nebraska
lead OTHER
Principal Investigators
-
Vijaya Raj Bhatt, MBBS,MS · University of Nebraska
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-04-09
- Primary Completion
- 2032-03-25
- Completion
- 2033-03-25
Countries
- United States
Study Locations
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