Understanding the Post-Surgical Non-Small Cell Lung Cancer Patient's Symptom Experience

Summary

Among 13 core symptoms across 3,106 breast, colorectal, prostate, and lung cancer patients, persons with lung cancer were the most symptomatic, with moderate to severe fatigue being reported with the greatest prevalence. This is a proposed randomized controlled trial of a novel rehabilitative intervention for persons with non-small cell lung cancer after surgery that promotes self-management of cancer-related fatigue (CRF) and is practical, portable, low cost, and safe. The results of the study will provide a novel exercise intervention, and its optimal timing, that helps a vulnerable population by reducing CRF severity and fatigability and is applicable to nearly all post-thoracotomy lung cancer patients.

Conditions

• Fatigue
• Self Efficacy
• Quality of Life
• Physical Activity
• Lung Cancer
• Non-Small Cell Lung Cancer

Interventions

BEHAVIORAL

Light Physical Activity 1

Light (mild) physical activity program that corresponds with normal every day activities of daily living (\< 3.0 metabolic equivalents, METs), with a time commitment starting at 5 minutes a day 5 days a week gradually increasing to 30 minutes a day 5 days a week as you are able by week 6 as guided by your Registered Nurse researcher. The program begins approximately within one week after discharge from the hospital with the physical activity program starting approximately within the first week post-discharge from the hospital.

BEHAVIORAL

Light Physical Activity 2

Light (mild) physical activity program that corresponds with normal every day activities of daily living (\< 3.0 metabolic equivalents, METs), with a time commitment starting at 5 minutes a day 5 days a week gradually increasing to 30 minutes a day 5 days a week as you are able by week 6 as guided by your Registered Nurse researcher. The program begins approximately within one week after discharge from the hospital with the physical activity program starting approximately 7 weeks post-discharge from the hospital.

BEHAVIORAL

Support Education Activity

Participate in a supportive cancer-related education activity including a direct 10 - 15 minute phone conversation with a Registered Nurse researcher each week for 6-weeks after returning home from the hospital. Wear a pedometer each day of the study. Recording pedometer steps in the daily diary each day.

Sponsors & Collaborators

• Corewell Health West

  collaborator OTHER

• National Cancer Institute (NCI)

  collaborator NIH

• The Methodist Hospital Research Institute

  collaborator OTHER

• University of Nebraska

  lead OTHER

Principal Investigators

• Amy J Hoffman, PhD, RN · University of Nebraska

Study Design

Allocation

RANDOMIZED

Purpose

OTHER

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2019-06-04

Primary Completion

2023-11-01

Completion

2023-11-01

Countries

• United States

Study Locations