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Effect of Vitrification and Warming Media on Pregnancy Rates in the Context of Oocyte Donation

NCT07288866 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 111

Last updated 2026-01-28

No results posted yet for this study

Summary

Vitrification has become the gold standard for oocyte and embryo cryopreservation. Several commercial kits are available on the market, some are designed for specific developmental stages (e.g. oocytes, zygotes, cleavage-stage embryos or blastocysts) and others are suitable for several stages, therefore termed "universal". Oocytes, cleavage-stage embryos and blastocysts display different levels of resistance to cryopreservation, due to stage-specific properties. While the composition and the exposition protocol of stage specific media are optimized for specific developmental stages, "universal" media display a single composition, therefore exposition protocols should be adapted to each specific developmental stage to ensure optimal survival rates.

The main objective of this study is to determine whether the shift from "oocyte specific" vitrification and warming media to "universal" media has an impact oocyte survival, embryological and clinical outcomes.

Conditions

Interventions

OTHER

Vitrification and warming media for oocyte vitrification

Different combinations of the vitrification and warming media were used for oocyte vitrification procedure in the context of oocyte donation

Sponsors & Collaborators

  • University Hospital, Clermont-Ferrand

    lead OTHER

Principal Investigators

  • Florence Brugnon · University Hospital, Clermont-Ferrand

Eligibility

Min Age
18 Years
Max Age
43 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-07-01
Primary Completion
2020-07-02
Completion
2021-08-01

Countries

  • France

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07288866 on ClinicalTrials.gov