Investigation of Pathogenic Gut Microbiota Patterns in Anxiety, Depression and Panic Disorders

NCT07268729 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2026-04-29

No results posted yet for this study

Summary

This study aims to investigate the etiology of anxiety, depression, and panic disorders, providing new evidence and insights into the root causes and effective treatments, potentially offering a novel approach to achieving complete recovery.

Conditions

Interventions

DIAGNOSTIC_TEST

H pylori stool test

Participants will provide a stool sample for noninvasive testing to detect the presence of Helicobacter pylori bacteria. The test will be performed using a validated laboratory assay that identifies H. pylori antigens in stool. Results will be used to assess potential associations between H. pylori infection, gut microbiome composition, and symptoms of anxiety or depression. The test is diagnostic only and does not involve administration of any drug or treatment.

DIAGNOSTIC_TEST

Bacterial stool analysis

Participants will provide stool samples for microbiome sequencing using a validated laboratory assay. The analysis will characterize bacterial taxa within the gut microbiome and identify potential pathogenic species. Sequencing results will be correlated with psychological assessments and clinical measures to investigate relationships between gut microbial composition and symptoms of anxiety, depression, and panic disorder.

Sponsors & Collaborators

  • MedBliss Research Network

    collaborator UNKNOWN
  • University of Toronto

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-10
Primary Completion
2026-01-25
Completion
2026-02-10

Countries

  • Canada

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07268729 on ClinicalTrials.gov