Gut Microbiota in IBD With Comorbid Depressive Disorder
NCT07252427 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2026-01-23
Summary
Inflammatory bowel disease (IBD) is often comorbid with depressive disorder, and the development and progression of both conditions are closely related to the composition of gut microbiota and metabolites. However, studies investigating their comorbidity using microbiome and metabolomics approaches remain limited.
This study aims to investigate the diversity changes in the gut microbiome and metabolome of patients with comorbid IBD and depressive disorder through multi-omics approaches, to identify specific microbial and metabolic signatures associated with the comorbidity of these two conditions, and to provide a molecular basis for elucidating the underlying mechanisms.
Conditions
- Inflammatory Bowel Disease
- Depressive Disorder
Interventions
- OTHER
-
Not applicable- observational study
observational study with no assigned intervention
Sponsors & Collaborators
-
Fang Tang
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-03-16
- Primary Completion
- 2027-11-30
- Completion
- 2027-11-30
Countries
- China
Study Locations
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