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Sex-specific Differences in the Association Between Leg Fat and Diabetes Risk

NCT07261800 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 542

Last updated 2025-12-03

No results posted yet for this study

Summary

This study investigates the association between LFP, VAT and T2DM using DXA in 542 adults. We apply penalized regression, generalized additive models (GAM), and causal mediation analysis to explore whether higher LFP reduces diabetes risk and whether this effect is mediated by VAT. Sex-specific analyses further clarify the biological differences in adipose distribution. The findings aim to improve understanding of fat distribution and metabolic health.

Conditions

Interventions

OTHER

Not Applicable - Retrospective study

Not Applicable - Retrospective study

Sponsors & Collaborators

  • Qianfoshan Hospital

    lead OTHER

Principal Investigators

  • Xuan Song · Shandong First Medical University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-31
Primary Completion
2025-02-12
Completion
2025-08-10

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07261800 on ClinicalTrials.gov