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Effect of a Short-term Multi-strain Probiotic Supplementation in Endurance Athletes

NCT07252778 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-11-28

No results posted yet for this study

Summary

The aim of this project is to evaluate and identify the effect of a short-term 2-week multi-strain probiotic (MPRO) supplementation on the exercise-associated gastrointestinal (GI) symptoms and perturbations in high level female athletes of the Polish national team during strictly controlled conditions of a training camp, based on recommendations for best practices for probiotic (PRO) research in athletes and assessment of EX-associated GI perturbations.

Conditions

  • Sports Nutrition
  • Biochemical Markers
  • Exercise Performance
  • Aerobic Capacity
  • Supplementation

Interventions

DIETARY_SUPPLEMENT

MPRO supplementation

In the experimental procedure each athlete will be supplemented with a certificated, commercially available MPRO supplement SANPROBI® Barrier (Bifidobacterium lactis W52, Lactobacillus brevis W63, Lactobacillus casei W56, Lactococcus lactis W19, Lactococcus lactis W58, Lactobacillus acidophilus W37, Bifidobacterium bifidum W23, Bifidobacterium lactis W51, Lactobacillus salivarius W24). The supplement will be provided in the capsule form and will be taken twice a day \[4 capsules of MPRO/day (2×10to9 CFU/g, 500 milions CFU/capsule) in two servings/day (2x2 capsules\].

DIETARY_SUPPLEMENT

Placebo treatment

In the control procedure each athlete will be supplemented with a placebo (PLA). The PLA group will receive corn starch mixed with maltodextrins. The PLA will be provided in the capsule form and will be taken twice a day (2x2 capsules/day).

Sponsors & Collaborators

  • Institute of Human Genetics, Polish Academy of Sciences

    collaborator UNKNOWN

  • Krzysztof Durkalec-Michalski

    lead OTHER

Principal Investigators

  • Krzysztof Durkalec-Michalski, PhD · Department of Sports Dietetics, Poznan University of Physical Education Poznań

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
16 Years
Max Age
50 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-11-20
Primary Completion
2027-06-01
Completion
2027-06-30

Countries

  • Poland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07252778 on ClinicalTrials.gov