MedTrace Logo

Fecal Microbiota Transplantation for Irritable Bowel Syndrome

NCT03613545 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2021-08-03

No results posted yet for this study

Summary

Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. FMT has a higher cure rate than standard antibiotic treatment for recurrent Clostridium difficile infections,and shows promising results in Inflammatory bowel disease（IBD）.However, few studies have evaluated whether FMT is effective to treat Irritable bowel syndrome(IBS).The investigators propose to determine the efficiency and safety of FMT in patients with Irritable bowel syndrome.

Conditions

  • Irritable Bowel Syndrome
  • Fecal Microbiota Transplantation

Interventions

PROCEDURE

fecal microbiota transplantation

200 mL of prepared fecal microbiota suspension from heathy donors' fresh feces was injected into the colon

PROCEDURE

Infusion of sham

Infusion of sham

DRUG

probiotics, antibiotics or antidepressants

Drugs such as probiotics, antibiotics, antidepressants

Sponsors & Collaborators

  • Guangzhou First People's Hospital

    lead OTHER

Principal Investigators

  • Hongli Huang, MM · Guangzhou First People's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-08-10
Primary Completion
2028-12-31
Completion
2030-12-31

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03613545 on ClinicalTrials.gov