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Phase I Trial of pH Resections of GBM at VA

NCT07218367 · Status: NOT_YET_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2026-02-13

No results posted yet for this study

Summary

Glioblastoma is an infiltrating tumor that is difficult to visualize in surgery and on standard images. A special pH (acid-base) related magnetic resonance imaging (MRI) has been developed to better see infiltrating tumor. In this safety study, the investigators will carry out increased levels of pH based resections of infiltrating tumor to assess the tolerability in VA populations.

Conditions

Interventions

PROCEDURE

pH MRI based resection of GBM

This will require a chemical exchange saturation transfer MRI followed by surgical resection based on this MRI.

Sponsors & Collaborators

Principal Investigators

  • Kunal S Patel · VA Greater Los Angeles Healthcare System, West Los Angeles, CA

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-07-01
Primary Completion
2031-07-01
Completion
2031-07-01

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07218367 on ClinicalTrials.gov