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Transient Ischemic Attack (TIA) and Spoken Language

NCT07206433 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2025-10-03

No results posted yet for this study

Summary

Transient Ischaemic Attack (also known as TIA or 'mini-stroke') affects about 46,000 people in the UK each year. It is assumed that people recover fully within 24 hours. However, subtle problems with speaking, and confidence with their communication skills can be long-term. This project will be the first in depth exploration of speaking abilities after recent TIA where there seemed to be a full recovery.

The researchers will look for 90 volunteers for detailed testing. Thirty people who have had a TIA for the first time. For comparisons, the researchers will also include 60 volunteers without TIA (30 treated to prevent TIA and stroke; 30 who do not receive prevention treatments).

Aims and methods:

1. To find out if TIA makes speaking difficult.

People will complete speaking tasks in a quiet place. For example, people will be asked to tell us about their weekend, what they think about climate change.
2. To find out if people are concerned about their speech and other thinking skills after TIA.

People will fill in questionnaires to help us look into these issues.
3. To find out if speaking abilities and people's own views of their communication change over time (about three months after the TIA).

Discovering new knowledge about spoken communication after a TIA diagnosis could change the course of TIA research and care across health professions (speech-language therapy, psychology, audiology, neurology). Future studies could use speaking tasks to scrutinise further the complexity of subtle communication problems after TIA and determine which individuals are likely to have these problems. The project will raise understanding of these issues, enabling affected individuals to seek professional support. Finally, it will also guide development of new TIA recommendations and treatments for these problems thus improving people's quality of life.

Conditions

  • TIA (Transient Ischemic Attack)

Sponsors & Collaborators

  • Northumbria Healthcare NHS Foundation Trust

    collaborator OTHER

  • Newcastle University

    lead OTHER

Principal Investigators

  • Christos Salis, PhD · Newcastle University

  • Lisa Shaw, MD · Newcastle University

  • Christopher Price, MD · Newcastle University

  • Mahmoud Kargar, MSc · Newcastle University

Eligibility

Min Age
40 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2027-06-30
Completion
2027-06-30

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07206433 on ClinicalTrials.gov