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Remote Ischemic Conditioning in Aneurysmal SAH

NCT06032533 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2025-10-03

No results posted yet for this study

Summary

The goal of this clinical trial is to examine the effect of limb occlusion therapy (remote ischemic conditioning, RIC) in subjects with aneurysmal subarachnoid hemorrhage.

The main question it aims to answer is whether RIC can improve long-term recovery in participants with aneurysmal subarachnoid hemorrhage.

Researchers will compare levels of functional independence in participants in the RIC-group to participants in the sham-group.

Conditions

  • Subarachnoid Hemorrhage, Aneurysmal
  • Delayed Cerebral Ischemia

Interventions

DEVICE

Remote Ischemic Conditioning with Automatic Tourniquet Device

5 Cycles of Remote Ischemic Conditioning performed on the leg. One cycle consists of 5 minutes of arterial occlusion followed by 5 minutes of reperfusion. The above is repeated daily for 14 days or until patient is discharged. Patients are randomized to either active Remote Ischemic Conditioning or Sham-treatment.

DEVICE

Sham Remote Ischemic Conditioning with Automatic Tourniquet Device

5 Cycles of sham-treatment performed on the leg. One cycle consists of 5 minutes of sham-treatment followed by 5 minutes of pause. The above is repeated daily for 14 days or until patient is discharged. Patients are randomized to either active Remote Ischemic Conditioning or Sham-treatment.

Sponsors & Collaborators

  • Aarhus University Hospital

    lead OTHER

Principal Investigators

  • Grethe Andersen, Prof., MD · Department of Neurology, Aarhus University Hospital

  • Arzu Bilgin-Freiert, MD, PhD · Department of Neurosurgery

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-09
Primary Completion
2027-11-30
Completion
2027-11-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06032533 on ClinicalTrials.gov