Nocturnal Blood Pressure Dipping and Ventricular Repolarization in Hypertension
NCT07200856 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 140
Last updated 2025-10-01
Summary
The primary aim is to determine whether non-dipping status is associated with adverse repolarization markers and impaired myocardial mechanics compared to dipper hypertensive patients. Secondary analyses will compare these findings among resistant vs. non-resistant and controlled vs. uncontrolled hypertensive groups. This study may provide new insights into the prognostic significance of blood pressure dipping patterns in hypertensive patients.
Conditions
- Hypertension
- Blood Pressure Monitoring, Ambulatory
- Circadian Rhythm
- Electrocardiography
- Ventricular Function
Interventions
- OTHER
-
Nocturnal Blood Pressure Dipping
Patients will be classified as dippers (≥10% nocturnal BP fall) or non-dippers (\<10% nocturnal BP fall) based on 24-hour ambulatory blood pressure monitoring.
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Mohamed Aboel-Kassem Farghal Abdelmegid · Cardiology Department - Assiut University
-
Noha Mohamed Gamal Hashem · Cardiology Department - Assiut University
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-01
- Primary Completion
- 2026-10-01
- Completion
- 2027-01-01
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