Nocturnal Blood Pressure and Hypertension - Central and Peripheral 24-h Blood Pressure.
NCT02078765 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2014-10-09
Summary
A new study have shown that high night time blood pressure (BP) and/or non-dipping (lack of fall in BP during night time) is a strong predictor for the risk of cardiovascular disease and mortality in patients with hypertension. Three factors seem to affect the night time BP: chronic kidney disease, obstructive sleep apnea (OSA) and the way ambulatory blood pressure is monitored.
Hypothesis:
Central 24-h blood pressure monitoring is a better way of monitoring blood pressure than conventional peripheral monitoring.
In hypertension, chronic kidney disease and obstructive sleep apnea (OSA) the night time blood pressure is elevated, and is OSA the elevation is correlated to the severity of OSA.
In OSA the kidneys handling of salt and water is disturbed. In OSA there is disturbances in hormonal balance.
Conditions
- Hypertension
- Chronic Kidneys Disease
- Obstructive Sleep Apnea
Sponsors & Collaborators
-
Erling Bjerregaard Pedersen
lead OTHER
Eligibility
- Min Age
- 55 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-01-31
- Primary Completion
- 2015-12-31
- Completion
- 2017-12-31
Countries
- Denmark
Study Locations
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