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Immunometabolism of Exercise

NCT07188389 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 102

Last updated 2026-05-01

No results posted yet for this study

Summary

This study aims to examine the effects of acute aerobic exercise and cardiorespiratory fitness on cellular metabolism of CD8+ T cells and regulatory T cells (Tregs) found in the peripheral blood of humans. In addition, the study will investigate whether the effects of exercise differ based on exercise intensity, as well as whether the effects of exercise and fitness differ between subpopulations of CD8+ T cells and Tregs. Finally, the study aims to examine whether exercise- and fitness-induced changes in cell metabolism relate to changes in cell function.

Conditions

  • No Condition, Assessment of Healthy Volunteers

Interventions

BEHAVIORAL

Acute exercise-moderate intensity

30 minutes of cycling exercise at moderate (90% of first ventilatory threshold)

BEHAVIORAL

Acute effects-heavy intensity

Participants will cycle 30 minutes at heavy (110% of first ventilatory threshold) intensity

Sponsors & Collaborators

  • University of Houston

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-03-01
Primary Completion
2025-04-02
Completion
2025-04-03

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07188389 on ClinicalTrials.gov