Lidocaine, Paracetamol, and Dexmedetomidine for Rocuronium Injection Pain

NCT07169227 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 170

Last updated 2025-09-11

No results posted yet for this study

Summary

Propofol and rocuronium may cause pain during intravenous injection. Various pharmacological agents are used to reduce the incidence and severity of injection pain. Among the most commonly used agents for this purpose are lidocaine, various opioids, ketamine, paracetamol, and dexmedetomidine. The aim of this study was to evaluate the comparative effect of intravenous dexmedetomidine and paracetamol versus lidocaine in preventing propofol- and rocuronium-induced pain during anesthesia induction.

Conditions

  • Propofol Injection Pain
  • Rocuronium Injection Pain

Interventions

DRUG

Lidocaine %2 ampoule

Patients who were administered 40 mg lidocaine.

DRUG

Dexmedetomidine

Patients who were administered 0.25 mg/kg dexmedetomidine.

DRUG

paracetamol

Patients who were administered 50 mg paracetamol.

Sponsors & Collaborators

  • Baskent University

    lead OTHER

Principal Investigators

  • Sibel Çatalca, Dr. · Baskent University, Adana Dr. Turgut Noyan Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-09-30
Primary Completion
2025-10-31
Completion
2025-10-31

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07169227 on ClinicalTrials.gov