Lidocaine, Paracetamol, and Dexmedetomidine for Rocuronium Injection Pain
NCT07169227 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 170
Last updated 2025-09-11
Summary
Propofol and rocuronium may cause pain during intravenous injection. Various pharmacological agents are used to reduce the incidence and severity of injection pain. Among the most commonly used agents for this purpose are lidocaine, various opioids, ketamine, paracetamol, and dexmedetomidine. The aim of this study was to evaluate the comparative effect of intravenous dexmedetomidine and paracetamol versus lidocaine in preventing propofol- and rocuronium-induced pain during anesthesia induction.
Conditions
- Propofol Injection Pain
- Rocuronium Injection Pain
Interventions
- DRUG
-
Lidocaine %2 ampoule
Patients who were administered 40 mg lidocaine.
- DRUG
-
Dexmedetomidine
Patients who were administered 0.25 mg/kg dexmedetomidine.
- DRUG
-
Patients who were administered 50 mg paracetamol.
Sponsors & Collaborators
-
Baskent University
lead OTHER
Principal Investigators
-
Sibel Çatalca, Dr. · Baskent University, Adana Dr. Turgut Noyan Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-09-30
- Primary Completion
- 2025-10-31
- Completion
- 2025-10-31
Countries
- Turkey (Türkiye)
Study Locations
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