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BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention

NCT07162337 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-05-18

No results posted yet for this study

Summary

This research study is a prospective, single-arm clinical trial to assess the effect of a dietary intervention for more plant-based and less animal-based food intake on secondary bile acid production, gut microbiota, circulating biomarkers and gene expression associated with colonic bile acid receptor activation and colorectal cancer.

Conditions

  • Colorectal Cancer Prevention
  • Colorectal Adenoma

Interventions

BEHAVIORAL

Increased Plant-Based Diet and Decreased Animal-Based Diet

Self-regulated diet; increased plant-based foods with decreased animal-based foods

Sponsors & Collaborators

Principal Investigators

  • Andrew T. Chan, MD, MPH · Massachusetts General Hospital

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-09
Primary Completion
2027-03-31
Completion
2028-03-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07162337 on ClinicalTrials.gov