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Microplastics in Paraneoplastic and Intratumoral for Colorectal Cancer

NCT07063550 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2025-07-14

No results posted yet for this study

Summary

The objective of this study is to identify and characterize microplastics present in peritumoral and intratumoral tissues of colorectal cancer patients, and to investigate their associations with gut microbiome composition and metabolic profiles. By integrating microplastic analysis with metagenomic and metabolomic data, we aim to explore the potential impact of environmental microplastic exposure on tumor microenvironment alterations, microbial dysbiosis, and metabolic reprogramming in colorectal cancer.

Conditions

  • Colorectal Cancer (MSI-H)
  • Microplastic Exposure

Interventions

OTHER

exposure to microplastic

Microplastic content in cancerous and paracancerous tissues

Sponsors & Collaborators

  • Dong Peng

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-01
Primary Completion
2026-10-01
Completion
2026-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07063550 on ClinicalTrials.gov