Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy
NCT06957626 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 150
Last updated 2025-07-01
Summary
The characteristics of the intestinal microbiota in high-risk colorectal polyp recurrence and their relationship with disease pathogenesis have not yet been fully elucidated. This study aims to analyze the microbial community characteristics in the intestinal mucosal tissue of patients after polypectomy with recurrence of colorectal polyps. Additionally, this research holds significant importance for understanding the etiology of adenoma recurrence and develop a microbiota and metabolite-based predicting tool.
Conditions
- Colorectal Polyp
- Colorectal Cancer Recurrent
- Colorectal Adenoma
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Principal Investigators
-
Jing nan Li, MD, Ph.D · Peking Union Medical College Hospital
Eligibility
- Min Age
- 40 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-04-25
- Primary Completion
- 2026-04-30
- Completion
- 2026-04-30
Countries
- China
Study Locations
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