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Kaempferol Gel , Alkaline Phosphatase Activity , Bone Density Around Dental Implants

NCT07156799 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2025-09-05

No results posted yet for this study

Summary

Kaempferol gel was tested as a local adjunct during implant placement in 30 patients. Compared to controls, the Kaempferol group showed significantly higher ALP activity at 2 and 4 weeks and greater bone density gain after 6 months (40.73% vs. 33.21%). These findings suggest Kaempferol enhances early bone remodeling, improves peri-implant bone quality, and may allow earlier implant loading.

Conditions

  • Peri-implant Bone Healing and Osseointegration

Interventions

DRUG

Kaempferol Gel

Local topical application of Kaempferol gel into the implant site during one-stage delayed implant placement to enhance peri-implant bone healing and osseointegration.

Sponsors & Collaborators

  • Al-Azhar University

    lead OTHER

Principal Investigators

  • Dr. Nora Abdelgawad · Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-05
Primary Completion
2024-06-10
Completion
2024-12-07

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07156799 on ClinicalTrials.gov