A Study of DXC014 in Patients With Advanced Solid Tumors.
NCT07177937 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2026-04-24
Summary
This is a phase I, open-label, first-in-human clinical study designed to evaluate the safety, tolerability, MTD, DLT, RP2D, the PK characteristics, preliminary anti-tumor activity, the immunogenicity of DXC014 in patients with Advanced Solid Tumors.
Conditions
- Small Cell Lung Cancer
- Melanoma
- Prostate Cancer
- Other Advanced Solid Tumors
Interventions
- DRUG
-
DXC014
Dose Escalation DXC014, Cohort Expansion DXC014
Sponsors & Collaborators
-
Hangzhou DAC Biotechnology Co., Ltd.
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-03-03
- Primary Completion
- 2030-10-20
- Completion
- 2030-10-20
Countries
- China
Study Locations
More Related Trials
-
A Study of MHB042C in Patients With Advanced Solid Tumors
NCT07192107 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of HC006 in Subjects With Advanced Solid Tumors
NCT06304571 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of CSCJC3456 in Patients With Advanced Malignant Tumors
NCT06717750 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of RC108-ADC in Subjects With Advanced Malignant Solid Tumors
NCT04617314 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate ANS014004 in Participants With Locally Advanced or Metastatic Solid Tumors
NCT06307795 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of DB-1317 in Selected Advanced/Metastatic Solid Tumors
NCT07141706 ·Status: RECRUITING ·Phase: PHASE1
-
Dose Escalation and Dose Expansion Study of MDX2004 in Participants With Advanced Tumors
NCT07110584 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CD-001 in Patients With Advanced Solid Tumors
NCT06801470 ·Status: RECRUITING ·Phase: PHASE1
-
Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors
NCT06239194 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Decitabine in Treating Patients With Advanced Solid Tumors
NCT00030615 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I of XKH002 Injection in Patients
NCT06196762 ·Status: RECRUITING ·Phase: PHASE1
-
Study of Intravenous RXDX-107 in Patients With Solid Tumors
NCT02548390 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase 1 Study of HDM2017 in Advanced Solid Tumors
NCT07274085 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of HY-0102 in Patients With Advanced Solid Tumors
NCT06094777 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Study to Evaluate the Safety, Pharmacokinetics and Antitumor Activity of HC010 in Patients With Advanced Solid Tumors
NCT06307925 ·Status: RECRUITING ·Phase: PHASE1
-
Phase 1, First in Human, Open-Label, Dose-Escalation Study of 609A
NCT03950297 ·Status: UNKNOWN ·Phase: PHASE1
-
Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors
NCT05142592 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of DB-1202 Monotherapy in Advanced Solid Tumors
NCT05785728 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors
NCT06859762 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of HS-20122 in Patients With Advanced Solid Tumors
NCT06927570 ·Status: RECRUITING ·Phase: PHASE1
-
A Clinical Study Evaluating H1710 for Injection in Participants With Advanced Solid Tumors
NCT06992713 ·Status: RECRUITING ·Phase: PHASE1
-
A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors
NCT05159700 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
NCT03517488 ·Status: COMPLETED ·Phase: PHASE1
-
Phase 1/2 Clinical Study of HY07121 Powder for Solution for Infusion in Patients With Advanced Solid Tumors
NCT06639256 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of DM005 in Patients With Advanced Solid Tumors
NCT06515990 ·Status: RECRUITING ·Phase: PHASE1