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Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

NCT07126509 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-02-17

No results posted yet for this study

Summary

Purpose of the study: The main purpose of this research study is to see if a surgery procedure (limited partial pleurectomy and decortication) helps symptoms in people who have cancer that is unresectable that might not be able to be removed completely. This is called unresectable cancer. This study will also help the research team learn more about the types of symptoms and quality of life for people who have undergone this surgery, the number of complications following , and the time from surgery to starting other therapy. Th e study team also wants to see see the overall survival of people who have had this procedure as part of their care.

What will be done as part of research on this study:

* Surgery (Partial Pleurectomy - surgery to remove lining of lungs)
* The research team will also ask study participants questions about their symptoms through questionnaires at certain times after surgery.

How long this study will last:

Participation in this research (pre-surgery, surgery and follow-up) will last for about 2 years.

Confidentiality: All personal information will be kept confidential, and data will be used only for research purposes.

Contact Information: For more information about this study, please contact [email protected]

Conditions

  • Mesothelioma
  • Mesothelioma; Lung
  • Mesotheliomas Pleural
  • Mesothelioma Malignant Advanced
  • Mesothelioma, Malignant

Interventions

PROCEDURE

Partial Pleurectomy

A partial pleurectomy is a surgical procedure where part of the pleura, the lining of the lung cavity, is removed. This may be done to remove tumors, excess tissue, or to treat lung complications.

Sponsors & Collaborators

  • University of Chicago

    lead OTHER

Principal Investigators

  • Darren Bryan, MD · University of Chicago

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-02
Primary Completion
2028-12-01
Completion
2028-12-01

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07126509 on ClinicalTrials.gov