Total Intravenous Anesthesia in Patients Undergoing Craniotomy

NCT07105618 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 108

Last updated 2026-05-06

No results posted yet for this study

Summary

Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.

Conditions

  • Anesthesia

Interventions

DRUG

Dexmedetomidine

Dexmedetomidine as an adjunct to total intravenous anesthesia.

DRUG

Fentanyl

Fentanyl as an adjunct to total intravenous anesthesia.

DRUG

Magnesium

Magnesium sulphate as an adjunct to total intravenous anesthesia.

Sponsors & Collaborators

  • Zagazig University

    lead OTHER_GOV

Principal Investigators

  • Fatma Mahmoud Ahmed, MD · Department of Anesthesia, Intensive Care & Pain Management, Zagazig University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-10
Primary Completion
2026-08-31
Completion
2027-04-30

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07105618 on ClinicalTrials.gov