A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

NCT07098611 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 470

Last updated 2026-05-05

No results posted yet for this study

Summary

Liberation from mechanical ventilation involves three steps: weaning, readiness assessment, and extubation. Readiness is determined using clinical criteria such as improvement of the underlying condition, hemodynamic stability, and adequate respiratory effort. Successful extubation is defined as not requiring invasive support within 48 hours. Due to the complexity of ICU patients, various clinical parameters and multi-component scores have been developed to predict extubation success. This study aims to develop and evaluate a multi-component score, the Readiness for EXtubation score (REXs), to predict extubation readiness in ICU patients under invasive mechanical ventilation.

Conditions

  • Ventilator Weaning
  • Respiration, Artificial
  • Respiratory Failure
  • Extubation Readiness
  • Extubation Failure
  • Extubation Succeeded
  • Intensive Care Patients Invasively Ventilated
  • Weaning Invasive Mechanical Ventilation

Sponsors & Collaborators

  • International Association of Non Invasive Ventilation

    collaborator UNKNOWN
  • International Academy of Non Invasive Ventilation

    collaborator UNKNOWN
  • International College of Experts of Non Invasive Ventilation

    collaborator UNKNOWN
  • Medipol University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-06-15
Primary Completion
2026-12-30
Completion
2026-12-30

Countries

  • Chile
  • Egypt
  • Iran
  • Italy
  • Spain
  • Turkey (Türkiye)

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07098611 on ClinicalTrials.gov