Manipulating the Peri-Infarct Area Using Maraviroc to Enhance Motor Skills After Stroke
NCT07080567 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2025-08-12
Summary
MASTER is a single-center, patient and investigator-blinded, Randomized Controlled Trial (RCT) to compare the efficacy of Maraviroc, a C-C chemokine receptor 5 (CCR5) antagonist, against placebo regarding motor function and motor learning skills in the first 3 months after ischemic stroke.
Conditions
- Ischemic Stroke
- Stroke
- Stroke Acute
Interventions
- DRUG
-
Maraviroc
Maraviroc (300mg) twice daily for 90 days
- DRUG
-
Mannitol
Placebo intervention
Sponsors & Collaborators
-
Emmanuel Carrera
lead OTHER
Principal Investigators
-
Emmanuel Carrera, MD · Hôpitaux Universitaires Genève
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-07-14
- Primary Completion
- 2027-12-31
- Completion
- 2027-12-31
Countries
- Switzerland
Study Locations
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