Intra-arterial Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke
NCT02178657 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 76
Last updated 2024-02-07
Summary
This trial aims to test that intra-arterial injection of autologous bone marrow mononuclear cells in acute ischemic stroke patients is safe and improves neurological outcomes.
Conditions
Interventions
- DRUG
-
Autologous bone marrow mononuclear cell intra-arterial injection
Sponsors & Collaborators
-
Andalusian Initiative for Advanced Therapies
lead OTHER_GOV
Principal Investigators
-
Francisco Moniche, MD, PhD · Hospitales Universitarios Virgen del Rocio
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-04-30
- Primary Completion
- 2021-10-27
- Completion
- 2023-04-12
Countries
- Spain
Study Locations
More Related Trials
-
Human Umbilical Cord Blood Infusion in Patients with Acute Ischemic Stroke (AIS)
NCT06040476 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Umbilical Cord-derived Mesenchymal Stem Cell Infusion for Treating Acute Ischemic Stroke
NCT06518902 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Safety and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic Stroke
NCT00821821 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of the Penumbra™ System in Acute Middle Cerebral Artery (MCA) Stroke
NCT01133223 ·Status: WITHDRAWN ·Phase: PHASE2
-
Clinical Trial of Umbilical Cord Mesenchymal Stem Cells in Subacute Ischemic Stroke
NCT07197606 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
RK-4 Intracalvariosseous Injection in Treatment of Acute Large Hemispheric Infarction
NCT07203521 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Phase I Clinical Safety Study About Human Umbilical Cord Blood Monocyte in the Acute Ischemic Stroke
NCT02433509 ·Status: COMPLETED ·Phase: PHASE1
-
Safety Study of PP-007 in Subjects With Acute Ischemic Stroke
NCT04677777 ·Status: COMPLETED ·Phase: PHASE1
-
MLC1501 Study Assessing Efficacy in STROke Recovery
NCT05046106 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
IMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care
NCT04242784 ·Status: COMPLETED
-
Randomized a Clinical Trial With Medical Device in Acute Ischemic Stroke
NCT07113184 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Safety of Escalating Doses of Intravenous Bone Marrow-Derived Mesenchymal Stem Cells in Patients With a New Ischemic Stroke
NCT01849887 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Cord Blood Infusion for Ischemic Stroke
NCT02397018 ·Status: COMPLETED ·Phase: PHASE1
-
Reparative Therapy in Acute Ischemic Stroke With Allogenic Mesenchymal Stem Cells From Adipose Tissue, Safety Assessment, a Randomised, Double Blind Placebo Controlled Single Center Pilot Clinical Trial
NCT01678534 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation to Assess Safety and Tolerability of DM199 in Subjects With Acute Ischemic Stroke
NCT03290560 ·Status: COMPLETED ·Phase: PHASE2
-
Argatroban Stroke Treatment - A Pilot Safety Study
NCT00268762 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Intra-Arterial Thrombolysis After SUCCESSful Reperfusion in Anterior Circulation Ischemic Stroke
NCT06768138 ·Status: RECRUITING ·Phase: PHASE3
-
Intravenous Thrombosis and Patients with Prior Ischemic Stroke Within 3 Months
NCT06841978 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Phase ⅡStudy of Pinocembrin Injection to Treat Ischemic Stroke
NCT02059785 ·Status: SUSPENDED ·Phase: PHASE2
-
Dual Thrombolytic Therapy With Mutant Pro-urokinase and Low Dose Alteplase for Ischemic Stroke
NCT04256473 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Intra-thrombus Plasmin (Human) In Acute Peripheral Arterial Occlusion
NCT01222117 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Mildronate for Acute Ischemic Stroke
NCT01800357 ·Status: UNKNOWN ·Phase: PHASE2
-
Methylprednisolone for Stroke With Large Infarct Core and Post-stroke Lymphocytopenia
NCT07202143 ·Status: RECRUITING ·Phase: PHASE3
-
Acute Basilar Artery Occlusion: Endovascular Interventions vs Standard Medical Treatment
NCT02441556 ·Status: COMPLETED ·Phase: NA
-
A Study to Evaluate the Efficacy and Safety of BIIB131 for Participants With Ischemic Stroke Between 4.5 and 24 Hours After Last Known Well
NCT05764122 ·Status: WITHDRAWN ·Phase: PHASE2