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Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

NCT07063732 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2025-07-14

No results posted yet for this study

Summary

The purpose of this trial is to investigate the effect of acute ketone monoester ingestion (0.6 g KME/kg body weight) on the occurrence of the ventilatory threshold and the subsequent response of blood velocity in cerebral arteries during a maximal exercise test at low altitude and high altitude.

Conditions

  • High Altitude Hypoxia
  • Exercise

Interventions

DIETARY_SUPPLEMENT

Ketone Monoester (KME)

0.6 g KME per kg body mass; \[R\]-3-hydroxybutyl \[R\]-3-hydroxybutyrate. (Delta G Ketone, TΔS, Oxford).

DIETARY_SUPPLEMENT

Placebo

Inert, calorie-free placebo drink that is taste-matched to the ketone monoester supplement

Sponsors & Collaborators

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-28
Primary Completion
2025-08-31
Completion
2025-08-31

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07063732 on ClinicalTrials.gov