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THE Effect of Tight Glycemic Control on Microvascular Complications in Type 2 Diabetes Mellitus

NCT07049601 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2025-07-03

No results posted yet for this study

Summary

The goal of this clinical trial is to learn the impact of tight versus less tight glycemic control on microvascular complications among Egyptian adults with uncontrolled T2DM. The main question it aims to answer is:

Does tight glycemic control improve or worsens microvascular complications of diabetes compared to less tight glycemic control?

Participants will:

* Be divided to two groups according to their HbA1c group A tight glycemic control and less tight glycemic control.
* Be followed for 6 months with clinical, laboratory, and fundoscopic evaluations performed at baseline and endpoint.

Conditions

Interventions

OTHER

Insulin Therapy

The effect of this intervention on HbA1c leading to either tight glycemic control HbA1c less than 7% or less tight glycemic control HbA1c less than 7.5%

OTHER

Antidiabetic therapy, lifestyle modification

Individualized adjustments in antidiabetic therapy, lifestyle modification, and monthly clinical follow-up.

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Professor of internal medicine and endocrinology · Ain Shams University

  • Assistant Professor of internal medicine and endocrinology · Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-05-11
Primary Completion
2023-10-01
Completion
2023-10-30

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07049601 on ClinicalTrials.gov