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Effects of Dietary Nitrate in Women With Secondary Amenorrhea

NCT07019129 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2025-09-24

No results posted yet for this study

Summary

Excessive exercise, disordered attitudes toward eating, physical and psychological stress, and/or hormonal imbalances may result in cessation of menstruation (secondary amenorrhea). The accompanying lack of estrogen may impair muscle power and oxygen recovery after exercise by reducing nitric oxide levels. The purpose of this study is to determine whether ingestion of beetroot juice containing nitrate, an alternative source of nitric oxide, can help reverse these changes.

Conditions

  • Secondary Amenorrhea

Interventions

DIETARY_SUPPLEMENT

Beetroot Juice - Active

Nitrate-rich beetroot juice

DIETARY_SUPPLEMENT

Placebo Beetroot Juice Without Nitrate

Nitrate-poor beetroot juice

Sponsors & Collaborators

  • Indiana University

    lead OTHER

Principal Investigators

  • Andrew R Coggan, PhD · Indiana University Indianapolis

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
44 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-05
Primary Completion
2026-05-31
Completion
2026-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07019129 on ClinicalTrials.gov