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Combined Blood Pressure Medication and Activity Scheduling for Low Mood

NCT07017023 · Status: RECRUITING · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 76

Last updated 2025-07-24

No results posted yet for this study

Summary

This study explores the effects of 7-day losartan (50mg) versus placebo with brief behavioural activation on emotional processing in young volunteers low in positive mood

Conditions

  • Emotional Processing
  • Mood

Interventions

DRUG

Losartan with BA

7-day losartan (Cozaar, 50mg; oral tablet) with 7-day BA

OTHER

Placebo with BA

7-day placebo (oral; microcellulose in identical capsules) with 7-day BA

Sponsors & Collaborators

  • University of Oxford

    lead OTHER

Principal Investigators

  • Andrea Reinecke, PhD · University of Oxford

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-08
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07017023 on ClinicalTrials.gov