MedTrace Logo

Lipopolysaccharide (LPS) Challenge in Depression

NCT03142919 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2025-07-02

Study results available
· View outcomes & findings →

Summary

LPS Challenge in Individuals with Major Depressive Disorder

Conditions

Interventions

BIOLOGICAL

Lipopolysaccharide

Lipopolysaccharide (LPS) derived from E. Coli group O 113:H10:K negative

BIOLOGICAL

Placebo

Saline solution

Sponsors & Collaborators

  • Laureate Institute for Brain Research, Inc.

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-09-07
Primary Completion
2020-12-01
Completion
2020-12-01
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03142919 on ClinicalTrials.gov