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Dynamic Learning in Depression

NCT02913898 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2020-06-16

No results posted yet for this study

Summary

This study will assess learning bias (the tendency to learn more from negative relative to positive outcomes) at baseline in 3 groups of participants (currently depressed, previously depressed and never depressed). It will then try to modify this bias using a simple computerised training task completed at home daily for 2 weeks. Outcome measures include symptoms of depression, cognitive measures (i.e. accuracy and reaction time during completion of tasks), pupillometry measures and salivary cortisol.

Conditions

Interventions

BEHAVIORAL

IBLT

Information bias learning task-- a computer based task in which positive information is more useful when learning how best to complete it

BEHAVIORAL

IBLT control

A control version of the IBLT task-- a computer based task in which both positive and negative information is useful when learning how to complete it

Sponsors & Collaborators

  • University of Oxford

    lead OTHER

Principal Investigators

  • Michael Browning, MB.BS · University of Oxford

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-11-01
Primary Completion
2020-06-03
Completion
2020-06-03

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02913898 on ClinicalTrials.gov