Health eHeart BioBank

Summary

The purpose of the Health eHeart BioBank is to collect and store specimen (e.g. blood, DNA, tissue) for future studies at the University of California, San Francisco (UCSF) that will help determine changes and identify molecular and genetic markers in the human body that might help increase our knowledge of heart disease and guide development of new diagnostic tools and treatments that may help rapidly detect heart disease and prevent and/or treat heart disease.

Conditions

• Heart Diseases
• Cardiac Diseases
• Vascular Diseases
• Cardiovascular Diseases

Interventions

PROCEDURE

Blood Draw

Participants will be asked to contribute approximately 36 mL of blood using standard procedures and obtained at the time of a clinically ordered routine blood draw or a study ordered blood draw. Participants may be asked to contribute additional blood samples over the course of their participation in the study.

PROCEDURE

Tissue Collection

If the participant is undergoing a clinically ordered procedure (e.g. heart surgery/biopsy/transplant), then they will be asked to contribute tissue to the study before any tissue is collected during the procedure. Most samples collected by the HeH BioBank will be tissue that would be normally discarded after the procedure.

PROCEDURE

DNA Collection

Participants will be asked to contribute their DNA for Whole Genome Sequencing (WGS) to help identify genetic markers of heart disease. DNA will be obtained at the time of the blood draw or obtained through DNA collection kits administered to participants who are unable or unwilling to undergo a blood draw.

OTHER

Medical Chart Review

Demographic, clinical, and pathologic information will be extracted from the participant's medical record.

Sponsors & Collaborators

• University of California, San Francisco

  lead OTHER

Principal Investigators

• Jeffrey E Olgin, MD · University of California, San Francisco

• Gregory Marcus, MD · University of California, San Francisco

• Vasanth Vedantham, MD · University of California, San Francisco

• Connor G O'Brien, MD · University of California, San Francisco

• James P Pirruccello, MD · University of California, San Francisco

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-04-01

Primary Completion

2035-12-31

Completion

2035-12-31

Countries

• United States

Study Locations