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Intraoperative Midazolam on Delirium Outcome of Elderly Patients

NCT06963112 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 612

Last updated 2025-09-25

No results posted yet for this study

Summary

This study was a multicenter, randomized, double-blind, placebo-controlled trial to treat elderly surgical patients with low-dose midazolam or placebo for anesthesia induction. The incidence of postoperative 7-day delirium was assessed and compared between two groups, to provide valuable reference for clinical practitioners in the use of midazolam in elderly surgical patients.

Conditions

Interventions

DRUG

Midazolam

The intervention group patients were given 2mg midazolam injection (Jiangsu Enhua Pharmaceutical Co., Ltd.) during anesthesia induction

DRUG

Saline

The control group patients were given 2 mL physiological saline.

Sponsors & Collaborators

  • Changhai hospital of Navy Medical University

    collaborator UNKNOWN

  • China-Japan Union Hospital, Jilin University

    collaborator OTHER

  • The First Affiliated Hospital of Nanchang University

    collaborator OTHER

  • The First Affiliate Hospital of Guangxi Medical College

    collaborator UNKNOWN

  • Second Hospital of Jilin University

    collaborator OTHER

  • Chinese PLA General Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-01
Primary Completion
2026-07-01
Completion
2026-08-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06963112 on ClinicalTrials.gov