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Effects of Endogenous GIP on Postprandial Blood Pressure in Healthy Individuals

NCT06934473 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2025-09-08

No results posted yet for this study

Summary

The present study investigates the postprandial role of endogenous glucose-dependent insulinotropic polypeptide (GIP) on cardiovascular haemodynamics, hormone responses, and hypotensive symptoms during a tilt test.

Conditions

  • Bloodpressure

Interventions

OTHER

GIP(3-30)NH2 / study tool

Selective antagonist of the GIPR, GIP(3-30)NH2

OTHER

Saline (NaCl 0,9 %) (placebo)

Placebo (NaCl 0,9%)

OTHER

GIP(1-42)

Agonist of the GIPR, GIP(1-42)

Sponsors & Collaborators

  • University Hospital, Gentofte, Copenhagen

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-21
Primary Completion
2026-01-31
Completion
2026-01-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06934473 on ClinicalTrials.gov